ODCs

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1 OMIM reference -
1 associated gene
No signs/symptoms info

PROTEIN INTERACTIONS: 1

2 OMIM references -
4 associated genes
6 signs/symptoms

Severe combined immunodeficiency due to CORO1A deficiency

Idiopathic juvenile osteoporosis


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	CORO1A	(0.76)	DKK1

Citations in the biomedical literature:

Severe combined immunodeficiency due to CORO1A deficiency		Idiopathic juvenile osteoporosis
	Synonym(s): - SCID due to CORO1A deficiency - SCID due to coronin-1A deficiency - Severe combined immunodeficiency due to coronin-1A deficiency		Synonym(s): - IJO - Juvenile osteoporosis

	Classification (Orphanet): - Rare genetic disease - Rare immune disease		Classification (Orphanet): - Rare bone disease - Rare developmental defect during embryogenesis - Rare genetic disease

	Classification (ICD10): - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -		Classification (ICD10): - Diseases of the musculoskeletal system and connective tissue -

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: neonatal/infancy Average age of death: - Type of inheritance: autosomal recessive		Epidemiological data: Class of prevalence: unknown Average age onset: childhood Average age of death: - Type of inheritance: autosomal dominant

	External references: 1 OMIM reference - No MeSH references		External references: 2 OMIM references - No MeSH references

Idiopathic juvenile osteoporosis
	Very frequent - Bone pain - Mutiple fractures / bone fragility - Osteoporosis / osteopenia / demineralisation / osteomalacia / rickets Frequent - Abnormal gait - Motor deficit / trouble Occasional - Kyphosis
Severe combined immunodeficiency due to CORO1A deficiency
(no data available)